NanoString
Developing In-situ DNA Hybridization Incubator for High Autofluorescence Tissue Sample
Fluorescence microscopy is a powerful tool for the spatial profiling of tissue samples and provides biological details at the high resolution up to single cell level and beyond. One common drawback in the approach is tissue autofluorescence background, which often overwhelms the target fluorescence signal and causes poor data quality. This student team worked to build a prototype module to reduce the tissue autofluorescence during sample preparation step using LED light illumination. They also focused on temperature and moisture control to achieve high efficiency for Nanostring in-situ DNA hybridization. Sample tests were performed to prove the functionality.
Faculty Adviser(s)
Christopher Neils, Bioengineering
Related News

Mon, 07/07/2025 | UW Mechanical Engineering
Capstone creations
Students displayed innovative capstone design projects at the 2025 expo.

Fri, 09/20/2024 | UW Civil & Environmental Engineering
Smarter irrigation for a greener UW
A new project combines satellite data with ground sensors to conserve water and create a more sustainable campus environment.

Mon, 09/09/2024 | UW Mechanical Engineering
Testing an in-home mobility system
Through innovative capstone projects, engineering students worked with community members on an adaptable mobility system.

Mon, 08/19/2024 | UW Mechanical Engineering
Students strive to ensure accurate AED shock dosage
ShockSafe, developed by students with the help of mentors from Philips and Engineering Innovation in Health (EIH), can distinguish between children and adults during cardiac arrest emergencies.