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Seattle Grand Challenges Summit

Speakers and Panelists

Hugh Chang, MS, MBA

Director, Special Initiatives within the Office of the President, PATH

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Hugh Chang's responsibilities include strategic planning and management of cross-program initiatives within PATH including recent activities in determining how equity investment in global health companies can increase the rate of innovation targeting populations in the developing world. Hugh has over 20 years experience in the development and marketing of technology-based products.

More about Hugh Chang

Hugh has worked in global health for the past 10 years as a technology advisor to the Global Health group at the Bill and Melinda Gates Foundation and as a program officer at PATH. He received a B.S. in Electrical Engineering from UC Davis, an MBA from UCLA, and an M.S. in Bioengineering from the University of Washington.


Jonathan Chang

Data Science Team Member, Facebook

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Jonathan Chang is a member of the Data Science team at Facebook. There he explores Bayesian probabilistic modeling, topic modeling, data mining, and their application to large-scale systems. Jonathan earned his B.S. in Electrical and Computer Engineering from Caltech in 2003, and inches ever closer to finishing his PhD from Princeton.


Edward F. Crawley, Sc.D.

Ford Professor of Engineering and Professor of Aeronautics and Astronautics and of Engineering Systems, Massachusetts Institute of Technology

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Dr. Crawley's recent research has focused on the domain of architecture, design and decision support in complex technical systems that involve economic and stakeholder issues. He is currently working with NASA on the design of its lunar and earth observing systems and recently co-chaired the committee reviewing the NASA Exploration Technology Development Program.

More about Edward Crawley

Dr. Crawley has served as chairman of the NASA Technology and Commercialization Advisory Committee, a member of the NASA Advisory Committee, and a member of the Presidential Advisory Committee on the Space Station Redesign. He is also a member of the Committee on Science, Engineering and Public Policy of the National Academies. Dr. Crawley has served on the boards and advisory boards of numerous entrepreneurial ventures and is the founder of several successful technology and biotech companies. Over the years, Dr. Crawley has received numerous teaching awards and and has remained active in the development and reform of engineering education. He currently serves as the Director of the Bernard M. Gordon - MIT Engineering Leadership Program, an effort to strengthen the quality of engineering leadership education.

Dr. Crawley received an SB (1976) and an SM (1978) in Aeronautics and Astronautics, and an ScD (1981) in Aerospace Structures from MIT. He was awarded the AIAA Structures, Structural Dynamics and Materials Award, the ASME Adaptive Structures Medal, and the NASA Public Service Medal. He is a Fellow of the AIAA and the Royal Aeronautical Society (UK), and is a member of three national academies of engineering: the Royal Swedish Academy of Engineering Science, the (UK) Royal Academy of Engineering, and the US National Academy of Engineering.


Bonnie J. Dunbar, Ph.D.

President and CEO, The Museum of Flight

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Dr. Bonnie J. Dunbar, President and CEO of The Museum of Flight, joined the Museum in October 2005. Dr. Dunbar retired from the NASA Johnson Space Center where she was Associate Director, Technology Integration and Risk Management for the Space Life Sciences Directorate (SLSD) of the NASA Johnson Space Center. SLSD is responsible for Astronaut Crew Health, Human Health Research for Space Exploration, Human Factor Design of Spacecraft and Life Support Requirements.

More about Bonnie Dunbar

A NASA Mission Specialist astronaut and veteran of 5 space flights, Dr. Dunbar has logged more than 50 days in space. She has served as the Payload Commander on two flights, including the first Space Shuttle docking mission to the Russian Space Station Mir.

Dr. Dunbar holds BS and MS degrees in Ceramic Engineering from the University of Washington, and a PhD in Mechanical/Biomedical Engineering from the University of Houston. Prior to working for NASA, she was a senior research engineer with Rockwell International Space Division, where she helped to develop the equipment and processes for manufacturing the thermal protection system for the Space Shuttle.

Dr. Dunbar is a member of the American Ceramic Society (Fellow), the National Institute of Ceramic Engineers, the Society of Women Engineers and the American Institute of Aeronautics and Astronautics (AIAA Fellow). She has been awarded the NASA Space Flight Medal, the NASA Exceptional Leadership Medal and the NASA Distinguished Service Medal. Dr. Dunbar is a member of the Royal Society of Edinburgh, and in 2002 was elected to the National Academy of Engineers.


Lewis S. (Lonnie) Edelheit, Ph.D.

Retired Senior Vice President, Research & Development
General Electric Company

Lonnie Edelheit photo

Under Dr. Lewis S. (Lonnie) Edelheit's leadership, GE introduced numerous new leadership products, including digital X-ray and advanced ultrasound medical imagers, high-efficiency turbines for power generation, advanced lighting and electronics-based appliances and weatherable plastics to name a few. Highlights of his tenure include significant advances in the introduction of high-technology into GE's services businesses, Internet applications and Corporate R&D's leadership of the design for Six Sigma quality and e-Engineering initiatives throughout the GE businesses.

More about Lonnie Edelheit

Dr. Edelheit began his professional career as a physicist at the GE R&D Center, where he made significant contributions to computed tomography (CT) x-ray systems. He transferred to GE Medical Systems, where he helped to move GE's radically new form of computed tomography x-ray scanner quickly to the marketplace. In 1986, Dr. Edelheit left GE to become president and CEO of Quantum Medical Systems, a company that pioneered color flow ultrasound for vascular imaging. He returned to GE in 1991 as manager of the R&D Center's Electronic Systems Research Center and in 1992 assumed leadership of Corporate R&D.

Dr. Edelheit is a member of the National Academy of Engineering, the Industrial Research Institute, and a Fellow of the American Physical Society. He is on advisory Boards of both the Physics and Bioengineering Departments of the University of Washington, Harvard Medical and Beth Israel Deaconess Research and Education Institute. He is Chairman of the Advisory board to the Energy and Environment Directorate at the Pacific Northwest National Laboratory. He has numerous publications and presentations.

Dr. Edelheit earned a B.S. degree in engineering physics and an M.S. degree and PhD in physics from the University of Illinois.


Michael Griffin, Ph.D.

King-McDonald Eminent Scholar and Professor of Mechanical and Aerospace Engineering, and Director, Center for System Studies, The University of Alabama in Huntsville

Michael Griffin. Photo credit: NASA/Renee Bouchard.

Michael Griffin is the King-McDonald Eminent Scholar and Professor of Mechanical and Aerospace Engineering, and the Director of the Center for System Studies at The University of Alabama in Huntsville. From 2005-09 he was the Administrator of NASA. Prior to re-joining NASA he was Space Department Head at the Johns Hopkins University Applied Physics Laboratory. He has also held numerous executive positions with industry, including President and Chief Operating Officer of In-Q-Tel, Chief Executive Officer of Magellan Systems, General Manager of Orbital Science Corporation's Space Systems Group, and Executive Vice President and Chief Technical Officer at Orbital.

More about Michael Griffin

Mike is member of the National Academy of Engineering and the International Academy of Astronautics, an Honorary Fellow of the American Institute of Aeronautics and Astronautics, a Fellow of the American Astronautical Society, and a Senior Member of the Institute of Electrical and Electronic Engineers. He is the recipient of numerous honors and awards, including the NASA Exceptional Achievement Medal, the AIAA Space Systems Medal and Goddard Astronautics Award, the National Space Club's Goddard Trophy, the Rotary National Award for Space Achievement, and the Department of Defense Distinguished Public Service Medal.

Mike obtained his B.A. in Physics from the Johns Hopkins University, which he attended as the winner of a Maryland Senatorial Scholarship. He holds Master's degrees in Aerospace Science from Catholic University, Electrical Engineering from the University of Southern California, Applied Physics from Johns Hopkins, Civil Engineering from George Washington University, and Business Administration from Loyola College of Maryland. He received his Ph.D. in Aerospace Engineering from the University of Maryland.


Alon Halevy, Ph.D.

Head, Structured Data Management Research, Google

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Alon Halevy heads the Structured Data Management Research group at Google. Prior to that, he was a professor of Computer Science & Engineering at the University of Washington in Seattle, where he conducted research on database and data integration systems.

More about Alon Halevy

Dr. Halevy co-founded Nimble Technology, one of the first companies in the Enterprise Information Integration space, and founded Transformic Inc., a company that created search engines for the deep web, which was acquired by Google in 2005. Dr. Halevy is a Fellow of the ACM, received the the Presidential Early Career Award for Scientists and Engineers (PECASE) in 2000, and was a Sloan Fellow (1999-2000). He received his Ph.D. in Computer Science from Stanford University in 1993.


Ed Lazowska, Ph.D.

Bill & Melinda Gates Chair in Computer Science & Engineering, University of Washington

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Ed Lazowska holds the Bill & Melinda Gates Chair in Computer Science & Engineering at the University of Washington. Lazowska received his A.B. from Brown University in 1972 and his Ph.D. from the University of Toronto in 1977, when he joined the University of Washington faculty. His research and teaching concern the design, implementation, and analysis of high performance computing and communication systems.

More about Ed Lazowska

Lazowska chaired the Computing Research Association Board of Directors from 1997-2001, the NSF CISE Advisory Committee from 1998-99, the President's Information Technology Advisory Committee from 2003-05, and the DARPA Information Science and Technology Study Group from 2004-06. He is a member of the Microsoft Research Technical Advisory Board, and serves as a board member or technical advisor to a number of high-tech companies and venture firms.

Lazowska is a Member of the National Academy of Engineering, a Fellow of the American Academy of Arts & Sciences, a Member of the Washington State Academy of Sciences, and a Fellow of the Association for Computing Machinery, the Institute of Electrical and Electronics Engineers, and the American Association for the Advancement of Science. He currently serves as the Director of the University of Washington eScience Institute, and as Chair of the Computing Community Consortium. Twenty-one Ph.D. students and twenty-three Masters students have completed their degrees working with him.


John Markoff

Correspondent, The New York Times

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John Markoff joined The New York Times in 1988 as a reporter for the business section. He writes for the science section from San Francisco. Prior to joining the Times, he worked for The San Francisco Examiner.

He has written about technology and science since 1977 covering technology and the defense industry for the Pacific News Service in San Francisco. Additionally, he was a reporter at Infoworld, the West Coast editor for Byte magazine, and wrote a column on personal computers for The San Jose Mercury News.

More about John Markoff

He has been a lecturer at the University of California at Berkeley School of Journalism and is an adjunct faculty member in Stanford University's journalism department, where he teaches a course on reporting on Silicon Valley.

The Times nominated him for a Pulitzer Prize in 1995, 1998, and 2000 and in 1987 he was nominated by The San Francisco Examiner. In 2005, with a group of Times reporters, he received the Loeb Award for business journalism. He shared the Society of American Business Editors and Writers Breaking News award.

In 2007 he was named a member of the International Media Council at the World Economic Forum. In the same year he was named a fellow of the Society of Professional Journalists, the organization's highest honor.

He is the co-author of The High Cost of High Tech. He also wrote Cyberpunk: Outlaws and Hackers on the Computer Frontier, with Katie Hafner. With Tsutomu Shimomura, he co-authored Take-down: The Pursuit and Capture of Kevin Mitnick, America's Most Wanted Computer Outlaw—by the Man Who Did It. And in 2005 What the Dormouse Said: How the Sixties Counterculture Shaped the Personal Computer Industry, by Mr. Markoff, was published.

He holds an undergraduate degree from Whitman College and attended graduate school at the University of Oregon.


Bruce Montgomery, M.D.

Senior Vice President, Respiratory Therapeutics at Gilead Sciences, Inc.

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Dr. Bruce Montgomery currently works as Senior Vice President, Respiratory Therapeutics at Gilead Sciences, Inc. Before his work with Gilead, Dr. Montgomery was the Founder and CEO of Corus Pharma of Seattle, a drug development company focusing on infectious disease and respiratory drugs. Corus Pharma was purchased by Gilead Sciences, Inc. in August of 2006. Until October 2000, Dr. Montgomery served as Executive Vice President of Research and Development at PathoGenesis Corporation.

More about Bruce Montgomery

Dr. Montgomery has extensive pharmaceutical company experience in drug development, operations and financing. Dr. Montgomery has been responsible for two complete drug approvals, started multiple other programs that have led to three additional FDA approvals. From 1985 to 1989, Dr Montgomery was co-inventor, and then led the effort to obtain FDA approval of aerosolized pentamidine, the second AIDS drug approved by the FDA.

In 1998, the Commissioner of the FDA recognized Dr. Montgomery with special citation for his industry leading acceleration in the development and approval of tobramycin solution for inhalation.

Dr. Montgomery received his Bachelor of Science in Chemistry in 1975 (Magna cum Laude, Outstanding Chemistry Major (Merck Award)), and Doctorate of Medicine in 1979 (Alpha Omega Alpha Honor Medical Society) from the University of Washington, Seattle. Dr. Montgomery is a board certified internist and pulmonologist.


Matthew O'Donnell, Ph.D.

Frank and Julie Jungers Dean of Engineering, University of Washington

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Matthew O’Donnell is the Frank and Julie Jungers Dean of Engineering at the University of Washington. Under his leadership, the College of Engineering created a new program in molecular engineering that includes the construction of a dedicated facility scheduled to open in 2012. He has advanced new energy and computational sciences research programs, grown the size and strength of the college through new faculty hires, and reinvigorated undergraduate programs through an emphasis on experiential learning.

More about Matthew O'Donnell

O’Donnell is a biomedical engineer with an interdisciplinary focus. An expert in ultrasound imaging, his research uses coherent energy sources for non-invasive biomedical imaging. His specific research interests include ultrafast optics, in-vivo microscopy, catheter imaging of coronary arteries, optoacoustic arrays, and elasticity and molecular imaging.

O’Donnell is currently the principal investigator on two National Institutes of Health grants dealing with applications of ultrasound and photoacoustic imaging. He holds 55 patents and has authored or coauthored more than 300 publications. O'Donnell is associate editor of the journal Ultrasonic Imaging, a fellow of both the IEEE and the American Institute for Medical and Biological Engineering, and a member of the American Physical Society. In February 2009, he was elected to the National Academy of Engineering.

O'Donnell received undergraduate and doctoral degrees in physics from Notre Dame. He has 10 years of private sector experience as a research and development physicist at the General Electric Company in New York. In 1990, O’Donnell joined the faculty of the University of Michigan as a professor of electrical engineering and computer science. He chaired that university’s biomedical engineering department from 1998 to 2006.


Nicholas A. Peppas, Sc.D.

Fletcher Stuckey Pratt Chair in Engineering
Professor of Chemical Engineering, Biomedical Engineering and Pharmacy
Chair, Department of Biomedical Engineering
Cockrell School of Engineering, The University of Texas at Austin

Nicholas Peppas photo

Nicholas A. Peppas is the Fletcher Stuckey Pratt Chair in Chemical Engineering, Biomedical Engineering and Pharmacy, and Chair of the Department of Biomedical Engineering at the University of Texas, Austin. He is a member of the Institute of Medicine of the National Academy of Sciences, the National Academy of Engineering, the French Academy of Pharmacy, and the Texas Academy of Medicine, Engineering and Sciences. Peppas is recognized as a world authority in biomaterials and pharmaceutical sciences and as the father of modern drug delivery for the development of biomedical and drug-delivery applications of polymer networks and hydrogels.

More about Nicholas Peppas

The multidisciplinary approach of his research blends modern molecular and cellular biology with engineering to generate next-generation systems and devices. He has been recognized with the Pierre Galletti Award from AIMBE as well as awards from AIChE (Founders Award, William Walker Award, Institute Lecture, Bioengineering Award, Materials Award), Society for Biomaterials (Founders and Clemson Awards), Controlled Release Society (Founders Award) and other Societies.

Dr. Peppas is a fellow of AIChE, APS, MRS, SFB, AAAS, BMES, AIMBE, and ASEE. He is the President of the International Union of Societies of Biomaterials Science and Engineering, the Chair-elect of the BME Chairs Council, and a member of the Board of the Biomedical Engineering Society. Peppas has served as President of the Society for Biomaterials, the Controlled Release Society, Chair of the College of Fellows of AIMBE, and Director of AIChE.

Dr. Peppas has published 1100 papers and 45 patents and has supervised the research of numerous postdocs and graduate students including 85 PhDs, 36 of them presently professors in other Universities. He holds a Dipl. Eng. from the National Technical University of Athens (1971), a Sc.D. from the Massachusetts Institute of Technology (1973), and honorary doctorates from the University of Ghent, Belgium, the University of Parma, Italy, and the University of Athens, Greece.


Suzie Pun, Ph.D.

Associate Professor of Bioengineering
Adjunct Associate Professor of Chemical Engineering
University of Washington

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Suzie Pun is the Robert F. Rushmer Associate Professor in the Department of Bioengineering at the University of Washington and a UW adjunct associate professor of chemical engineering. Prior to joining UW, Pun was a senior scientist at Insert Therapeutics. She earned doctoral and master's degrees in chemical engineering from the California Institute of Technology and bachelor's in chemical engineering from Stanford University. Pun's research interests include non-viral gene delivery, delivery of drugs and molecular contrast agents, and transport processes within cells.

More about Suzie Pun

Pun is particularly interested in understanding and overcoming the limitations in intracellular trafficking to improve drug delivery. Delivery vehicles developed in the Pun laboratory may find application in the treatment of neurodegenerative diseases and solid tumors, tissue engineering, and tumor targeting of molecular imaging agents.

Pun's awards include the National Science Foundation CAREER Award in 2005 and the Presidential Early Career Award for Scientists and Engineers (PECASE) in 2006.


Larry Smarr, Ph.D.

Founding Director of the California Institute for Telecommunications & Information Technology
University of California, San Diego

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Larry Smarr, the Harry E. Gruber Professor in the Jacobs School of Engineering Department of Computer Science and Engineering, joined the UCSD faculty in 2000 and became the founding director of the California Institute for Telecommunications and Information Technology (Calit2) in December 2000. Prior to UCSD, he was the founder and 15-year director of the National Center for Supercomputing Applications and the National Computational Science Alliance, both based at the University of Illinois, Champaign-Urbana (UIUC).

More about Larry Smarr

Smarr earned a Ph.D. in physics from the University of Texas at Austin in 1975, then did research at Princeton and Harvard before joining the UIUC faculty in 1979. Smarr is a member of the National Academy of Engineering, and a Fellow of the American Physical Society and the American Academy of Arts and Sciences. He was a member of the President's Information Technology Advisory Committee and served on the Advisory Committee to the Director of the National Institutes of Health and on the NASA Advisory Council. In 2006 he received the IEEE Computer Society Tsutomu Kanai Award for his lifetime achievements in distributed computing systems.


Catharine van Ingen, Ph.D.

Partner Architect, Microsoft Research

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Catharine van Ingen is a Partner Architect in the Microsoft Research eScience Research Group. Her research explores how database and related technologies can change collaborative research in the environmental sciences. Working with computer scientists at Lawrence Berkeley Laboratory and key biogeoscience researchers, she is one of the primary forces behind a shared global living sensor and field observation dataset of supporting carbon-climate synthesis research.

More about Catharine van Ingen

Her most recent project, MODISAzure, is a prototype cloud service that lowers the barrier to entry to using remote sensing imagery in such synthesis studies. Prior to joining Microsoft Research in 2005, Catharine was the Windows architect primarily responsible for storage management. She has worked in and around storage technology since writing her first ter(or)byte circa 1980 while working at Fermilab. She was also the system architect for an early 64-bit machine. Catharine holds a PhD in Civil Engineering from CalTech.