Upcoming Calendar Events

  • Oct 27: MolES Seminar: Edward Lyman, University of Delaware

    Mon Oct 27, 2014 2:30 pm - 3:30 pm | Monday, Oct. 27, 2014, 2:30 - 3:30 p.m. PDT The Molecular Structure of the Liquid Ordered Phase Mixtures of lipids and cholesterol have complex miscibility phase diagrams, including a region two fluid coexistence at physiological temperatures that is promoted by the presence of cholesterol. The cell membrane, which is rich in cholesterol, is known to be heterogeneous, with patches that share features with the cholesterol rich, "liquid ordered" phase of cell membranes. I will present our work toward understanding the thermodynamic basis of liquid-liquid phase separation in bilayer mixtures, and its connection to heterogeneity in cell membranes. 10 μsec all-atom molecular dynamics simulations, obtained on a unique supercomputing resource called "Anton," reveal substructures within the liquid-ordered phase of lipid bilayers.  These substructures are composed of saturated hydrocarbon chains packed with local hexagonal order, and separated by interstitial regions enriched in cholesterol and unsaturated chains. Lipid hydrocarbon chain order parameters calculated from the Lo phase are in excellent agreement with 2H NMR measurements; the local hexagonal packing is also consistent with 1H-MAS NMR spectra of the Lo phase, NMR diffusion experiments, and small angle X-ray- and neutron scattering. The data suggest a new interpretation of the condensed complex model, a thermodynamic model for liquid-liquid phase separation in membranes. Partitioning of transmembrane (TM) segments between Lo and Ld regions is proposed to be controlled by the balance of substructure within Lo, potentially offering a resolution of the "partitioning puzzle" --- that TM segments which partition into raft phases partition out of Lo. Campus location: Johnson Hall (JHN) Campus room: 102 Event sponsors: The weekly seminar series organized by Molecular Engineering and Sciences Institute provides a forum for bringing national and international leaders in nanoscale science and technology to campus, and for graduate students enrolled in our Dual Ph.D. program in Nanotechnology to present their research. The campus and public are welcome to attend.

  • Oct 27: Neuroscience Seminar Series

    Mon Oct 27, 2014 3:30 pm - 4:30 pm | Monday, Oct. 27, 2014, 3:30 - 4:30 p.m. PDT Tom Reh, Professor, University of Washington Department of Biological Structure; Adjunct, Department of Bioengineering; Adjunct, Department of Neurological Surgery speaking on "Regulation of retinal development by miRNAs:  It's about time" Campus location: Magnuson Health Sciences Center T (HST) Campus room: T-747 Event sponsors: Graduate Program in Neurobiology & Behavior More info: depts.washington.edu…

  • Oct 28: LEVITON Info Session

    Tue Oct 28, 2014 3:00 pm - 4:00 pm | Tuesday, Oct. 28, 2014, 3 - 4 p.m. PDT For EE majors.  Come find out more about job opportunities at Leviton. Campus location: Electrical Engineering Building (EE1) Campus room: 303 More info: www.leviton.com

  • Oct 28: CSE Lecture: Changing the World vs. Making Money

    Tue Oct 28, 2014 3:30 pm - 4:30 pm | Tuesday, Oct. 28, 2014, 3:30 - 4:30 p.m. PDT CSE Distinguished Lecture Series Speaker: Hadi Partovi (Co-founder of non-profit Code.org, Entrepreneur) Abstract: Computer Science is a field with limitless possibilities. It is often seen as the gateway to creating the next amazing tech startup, and some students are lured by the dream of riches - the hope of inventing the next Instagram-like billion-dollar overnight success. It is also, though, a field that lies at the heart of addressing many of our national and global challenges. Many of the ways in which Computer Science is changing our world involve bridging the brick-and-mortar "old" world world with the new world of tech, creating new opportunities not only to make lots of money, but also to have major social impact. As somebody who has been involved founding and advising tech startups, working at one of the largest companies, and also having founded a nonprofit, Hadi Partovi has a unique vantage point on how a career in computer science could be used to make money, for social impact, or for both, simultaneously. Undergraduates contemplating their careers should make a special effort to join the "regular" faculty and graduate student audience at this talk. Campus location: Paul G. Allen Center For Computer Science & Engineering (CSE) Campus room: Atrium More info: www.cs.washington.edu…

  • Oct 28: Environmental Innovation Practicum

    Tue Oct 28, 2014 4:00 pm - 5:50 pm | Tuesday, Oct. 28, 2014, 4 - 5:50 p.m. PDT Greening the Built Environment Speakers: - Hoby Douglass, Director, VP Sustainable Business Development, General BioDiesel - Sean Newsum, Director of Environmental Strategy, Boeing Campus location: PACCAR Hall (PCAR) Campus room: 292 Distributions: Internet, Intranet, Paccar Kiosks, Megaplex, Graduate Lounge and Web Page, Undergrad Intranet Facebook: www.facebook.com… More info: www.foster.washington.edu…

  • Oct 28: LEVITON Information Session

    Tue Oct 28, 2014 4:15 pm - 5:15 pm | Tuesday, Oct. 28, 2014, 4:15 - 5:15 p.m. PDT For ME majors.  Come find out more about job opportunities at Leviton. Campus location: Mechanical Engineering Building (MEB) Campus room: TBD More info: www.leviton.com

  • Oct 29: Kavli BRAIN Coffee Hour: Neuromuscular control & neuro. disorders

    Wed Oct 29, 2014 1:00 pm - 2:00 pm | Russell Building1414 NE 42nd Street, Suite 204Seattle, WA 98105 Wednesday, Oct. 29, 2014, 1 - 2 p.m. PDT Kat Steele is an assistant professor in the Department of Mechanical Engineering at the University of Washington. Abstract:  The human neuromuscular and musculoskeletal systems are complex, with many more actuators than degrees of freedom. This complexity gives us the ability to perform the many tasks of daily living, but also makes treatment after injury, such as in stroke or cerebral palsy, incredibly challenging. In this seminar we will explore how new tools in musculoskeletal simulation and synergy analysis can be used to probe both unimpaired control and pathologic movement after brain injury. Event sponsors: This lecture is sponsored by the Center for Sensorimotor Neural Engineering, with support from the Kavli Foundation.  Facebook: www.facebook.com… Twitter: twitter.com… More info: csne-erc.org

  • Oct 29: HCDE Speaker: Reflection in Engineering Education

    Wed Oct 29, 2014 4:30 pm - 5:30 pm | Wednesday, Oct. 29, 2014, 4:30 - 5:30 p.m. PDT Reflecting, or exploring the meaning of experiences and the consequences of the meanings for future action, is a form of thinking that warrants greater attention.  Reflection can be a means to improve performance, achieve goals, and even grapple with what one scholar (Robert Kegan) calls “the mental demands of modern life.” In this talk, Dr. Turns will discuss efforts to operationalize, understand, and support reflection.  As part of this, she will describe the activities of the recently funded Consortium to Promote Reflection in Engineering Education (a consortium of twelve higher education institutions).   She will also focus on how reflection connects to human centered design and HCI, and particularly the design opportunities that are related to reflection. About the Speaker Jennifer Turns is a Professor in the Department of Human Centered Design & Engineering and Director of the Laboratory for Human Centered Engineering Education. She researches the intersection of engineering education, cognitive/learning sciences, and user-centered design. Her engineering education work has focused on engineering design learning, knowledge integration, and disciplinary understanding, and has involved the use of a wide variety of research methods including verbal protocol analysis, concept mapping, and ethnography. Turns' ground-breaking research makes her one of the most highly- respected specialists in the engineering education field. Campus location: Mary Gates Hall (MGH) Campus room: 241 Event sponsors: Human Centered Design & Engineering, University of Washington Facebook: www.facebook.com… More info: hcde.uw.edu…

  • Oct 30: CSE Lecture: Simplicity in Search User Interfaces

    Thu Oct 30, 2014 3:30 pm - 4:30 pm | Thursday, Oct. 30, 2014, 3:30 - 4:30 p.m. PDT CSE Distinguished Lecture Series Marti Hearst (UC Berkeley) CSE Distinguished Lecture Series Thursday, October 30, 2014, 3:30pm EEB-105 Abstract: It is rare for a new user interface to break through and become successful, especially in information-intensive tasks like search, coming to consensus or building up knowledge. Most complex interfaces end up going unused. Often the successful solution lies in a previously unexplored part of the interface design space that is simple in a new way that works just right. In this talk I will give examples of such successes in the information-intensive interface design space, and attempt to provide stimulating ideas for future research directions. Campus room: EEB-105 More info: www.cs.washington.edu…

  • Oct 30: BioE Lecture: Reinterpreting the Genetic Code

    Thu Oct 30, 2014 3:30 pm - 5:00 pm | Thursday, Oct. 30, 2014, 3:30 - 5 p.m. PDT REINTERPRETING THE GENETIC CODE: FROM POLYMERS TO PROTEOMICS Presenter David A. Tirrell is the Ross McCollum-William H. Corcoran Professor of Chemistry and Chemical Engineering, and Director of the Beckman Institute, at the California Institute of Technology. Over the last decade, cells have been outfitted with modified translational machinery that enables the participation of an expanded set of amino acids in protein synthesis, and that allows scientists and engineers to “reinterpret” the genetic code by redefining codon assignments.  These developments have fostered a more unified view of the chemistry of natural and synthetic macromolecules and provided a basis for powerful new approaches to materials design and to temporally and spatially resolved analysis of biological processes.                        For more information contact Ms. Shirley Nollette (206) 685-2002 or nolletts@uw.edu.  Campus location: Magnuson Health Sciences Center T (HST) Campus room: T-625 Event sponsors: University of Washington Department of Bioengineering, Allan S. Hoffman Lecture

  • Oct 30: CEI Interdisc. Seminar: Cody Schlenker

    Thu Oct 30, 2014 4:00 pm - 5:00 pm | Thursday, Oct. 30, 2014, 4 - 5 p.m. PDT Charge dynamics at interfaces in next-generation energy conversion materials We study charge carrier dynamics in organic and hybrid solar cell materials by combining spectroscopy, time-resolved device measurements, and thin film structural probes. We describe how recombination mechanisms at organic/organic interfaces and hybrid/interfaces can be modulated by balancing energy landscape and hierarchical film structure. Our recent work also focuses on using spectroscopic tools with temporal and structural sensitivity to better understand the dynamics of charge generation in emerging solar cell materials, for example, hybrid organo metal halide perovskites. Our results bring new insight into the molecular properties that determine charge carrier dynamics and suggest new strategies for materials design focused on kinetically suppressing recombination losses. Bio: Cody Schlenker is the Washington Research Assistant Professor of Chemistry and Clean Energy. He earned his Ph.D. Materials, Physical, and Organic Chemistry from the University of Southern California, 2010, and worked as a postdoc in the Ginger Lab at UW until 2013. The Schlenker group integrates synthetic chemistry and physical chemistry to explore fundamental principles and dynamic interfacial processes that allow us to develop advanced materials design concepts for low-cost, high-efficiency energy conversion and storage devices.  Campus location: Electrical Engineering Building (EE1) Campus room: EEB 125 Event sponsors: The Clean Energy Institute Interdisciplinary Seminar Series was established to bring distinguished leaders in the field of clean energy to campus to present their research and meet students, postdocs, and faculty from departments across the Colleges of Arts & Sciences, Engineering, and the Environment. CEI seminars take place regularly throughout the quarter on Thursday afternoons.

  • Nov 3: MolES seminar: Junghae Suh, Rice

    Mon Nov 3, 2014 2:30 pm - 3:30 pm | Monday, Nov. 3, 2014, 2:30 - 3:30 p.m. PST Developing virus nanoparticle (VNP)-based gene delivery vectors  Delivering nucleic acid-based therapeutics into target cells specifically is a considerable biomedical challenge. Using concepts and tools from virology, protein engineering, and molecular biology, we are interested in developing virus nanoparticle (VNP)-based gene delivery vectors to tackle this challenge with a different perspective. In particular, we are building a toolkit of VNPs that can conduct basic biomolecular computation in order to mediate targeted delivery. We are in the initial stages of programming defined logic operators into the virus nanostructure and have successfully created VNP prototypes that are activated by proteolytic tumor biomarkers. Additionally, we are interested in building bionano devices that are hybrid structures of VNPs and proteins. For example, in one of our projects we are interested in creating VNPs that can be used for imaging and therapy simultaneously. Unfortunately, incomplete knowledge of capsid biology makes it difficult to rationally design brightly fluorescent and fully infectious viruses. To overcome this problem, we generated a platform gene library that was used to make large libraries of virus mutants displaying fluorescent proteins on the capsid and then selected for variants with desired infectivity and fluorescent properties. This platform library can be used in the future to create other types of VNP-protein hybrid devices. Collectively, our work aims to engineer VNPs in creative ways for potential use in a broad range of biomedical applications. Bio: Dr. Suh received her B.S. in Chemical Engineering at MIT and Ph.D. in Biomedical Engineering at Johns Hopkins School of Medicine. Before joining the Rice University department of Bioengineering as an assistant professor in 2007, she completed a two-year postdoctoral fellowship in the Laboratory of Genetics at the Salk Institute for Biological Studies. Her graduate research focused on understanding the interaction of nanoscale systems, either nature-derived or human-engineered, with complex biological environments in an effort to discover ruling paradigms that govern the performance of nanoparticles designed for biomedicine. Her postdoctoral research focused on studying how natural viruses interface with cellular machinery, particularly those that maintain homeostasis in the cell nucleus. Such studies should uncover new insights into how synthetic nanoparticle systems can be designed to yield the performance efficiencies rivaling that of viruses. Currently, Dr. Suh works at the interface of virology, biophysics, molecular biology, and protein engineering to investigate and create novel virus-based materials for various biomedical applications. By manipulating the “inputs” and “outputs” of virus nanoparticles (VNP), she endeavors to develop platform technologies that can be used as therapeutics for a broad range of human diseases. She was awarded the NSF CAREER Award and the MDACC Ovarian Cancer SPORE Career Development Program Award for her innovative work on reprogramming viruses as therapeutic platforms. Additionally, Dr. Suh was part of the multi-institutional team of investigators that was awarded an NIH Grand Opportunities grant aimed at investigating the intracellular transport of a variety of engineered nanomaterials used for biomedical applications. Campus location: Johnson Hall (JHN) Campus room: 102 Event sponsors: The weekly seminar series organized by Molecular Engineering and Sciences Institute provides a forum for bringing national and international leaders in nanoscale science and technology to campus, and for graduate students enrolled in our Dual Ph.D. program in Nanotechnology to present their research. The campus and public are welcome to attend.

  • Nov 3: HCDE Master's Info Session

    Mon Nov 3, 2014 5:30 pm - 6:30 pm | Monday, Nov. 3, 2014, 5:30 - 6:30 p.m. PST Join the Department of Human Centered Design & Engineering (HCDE) to learn more about the HCDE Master's degree. All sessions are held from 5:30-6:30 p.m. in Sieg Hall, Room 420, on the University of Washington campus in Seattle. Learn more and apply at hcde.uw.edu/ms. Campus location: Sieg Hall (SIG) Campus room: 420 Event sponsors: Human Centered Design & Engineering (HCDE) Facebook: www.facebook.com… More info: hcde.uw.edu…

  • Nov 4: MolES Seminar: Trends behind wearable electronics

    Tue Nov 4, 2014 11:00 am - 12:00 pm | Tuesday, Nov. 4, 2014, 11 a.m. - 12 p.m. PST Functional Nanomaterials and Nanofabrication Processes for Flexible Device Applications Wearable electronics is becoming a new paradigm for the next generation computing and electronic systems. Leading global companies such as Google, Samsung and Apple are investing huge efforts towards the development and commercialization of wearable and flexible electronic systems. The essential components for the wearable electronic systems are circuit components (eg. transistors and RFIC), display (eg. visual and tactile display), power devices (eg. battery and solar cells), sensors (biosensors and environment sensors), etc. In this talk, I will discuss recent trends and state-of-the-art technology in these component and systems for wearable electronics. Then, I will discuss various chemical and physical sensors that are being developed at our laboratory in KAIST. In specific, I will explain about (1) metal oxide nanowire based flexible gas sensors for toxic gases, (2) metal nanotube based flexible gas sensors for hydrogen gas, (3) photosensitive nanomaterial based flexible UV sensors and (4) metal nanowire / CNT based flexible and stretchable strain sensors for the human motion detection.  Bio: Professor Inkyu Park received his Ph.D. (mechanical engineering) at UC Berkeley in 2007. He received a B.S. and M.S. degrees (mechanical engineering) from KAIST in 1998 and UIUC in 2003, respectively. He worked as a research specialist at Berkeley Sensor and Actuator Center (BSAC) in 2007-08 and a visiting researcher at Hewlett Packard Lab in 2005-08. He is currently an associate professor at the department of mechanical engineering @ KAIST. He is an expert in the nanofabrication, sensing devices & systems and mechanical reliability of micro/nano systems. He has published more than 100 articles in international journals and conferences. He also received several awards including Hewlett Packard (HP) Open Innovation Research Award in 2009-2012 and Best Paper Award in IEEE NANO 2010  Campus location: Molecular Engineering (MOL) Campus room: 315 Event sponsors: The weekly seminar series organized by Molecular Engineering and Sciences Institute provides a forum for bringing national and international leaders in nanoscale science and technology to campus, and for graduate students enrolled in our Dual Ph.D. program in Nanotechnology to present their research. The campus and public are welcome to attend.

  • Nov 4: Shobe Prize info session: quick pitches

    Tue Nov 4, 2014 2:00 pm - 3:00 pm | Tuesday, Nov. 4, 2014, 2 - 3 p.m. PST Learn how to put together a quick pitch for your tech or design idea for the Shobe Prize competition.  Each team must have at least one matriculated student (undergraduate or graduate) enrolled in any of the UW departments involved in dub (dub.washington.edu). Campus location: Sieg Hall (SIG) Campus room: HCDE Design Lab (Sieg 233) Event sponsors: Human Centered Design & Engineering (HCDE) More info: www.hcde.washington.edu…

  • Nov 4: Lecture: Cell Biomechanics in Cardiovascular Health

    Tue Nov 4, 2014 7:00 pm - 8:30 pm | Tuesday, Nov. 4, 2014, 7 - 8:30 p.m. PST Join us for the second night of the 2014 Engineering Lecture SeriesGet a Grip: Cell Biomechanics in Cardiovascular Health Speakers: Nate Sniadecki, Associate Professor, Mechanical Engineering Nathan White, Adjunct Assistant Professor, Bioengineering Our cardiovascular system depends on active cells that stretch, contract and twitch to keep our bodies healthy. These cells create blood clots when we have an injury to prevent blood loss and help pump blood through our bodies during exercise. By studying the biomechanics of these cells, mechanical engineers and physicians at the UW are finding lifesaving solutions that improve blood clotting to help us heal from traumatic injuries. Come hear how their work is changing medicine at a cellular level. Campus location: Kane Hall (KNE) Campus room: 120 Event sponsors: UW College of Engineering and UW Alumni Association Facebook: www.facebook.com… Twitter: twitter.com… More info: engage.washington.edu…

  • Nov 5: Beyond Designing Systems for Users with Mark Haselkorn

    Wed Nov 5, 2014 4:30 pm - 5:30 pm | Wednesday, Nov. 5, 2014, 4:30 - 5:30 p.m. PST One of the most compelling directions for Human Centered Design & Engineering (HCDE) focuses on facilitating complex communities in the organization and use of their information sharing environment.  Co-designing this system of systems with a vast and diverse array of stakeholders requires HCDEers to exercise skills and engage in roles that expand beyond the skillset and roles often associated with interface and system design.  Examples from the ongoing Maritime Operations Information Sharing Analysis (MOISA) project are used to explore this exciting and rapidly evolving area of HCDE. About the Speaker Mark Haselkorn is a Professor in the Department of Human Centered Design & Engineering. Haselkorn leads University of Washington (UW) partnerships in the National Center for Cognitive Informatics & Decision Making in Healthcare, funded by the Office of the National Coordinator for Health Information Technology, as well as the Center of Excellence on Visual Analytics for Command, Control, and Interoperability Environments, funded by the Department of Homeland Security. He is Director of the Pacific Rim Visualization and Analytics Center, which has the mission of advancing visual analytics for the enhancement of distributed, collaborative cognition and decision-making for public safety and security. He also founded and directs the UW’s Interdisciplinary Program on Humanitarian Relief, a cross-campus program of research and education that works with the international humanitarian sector to improve logistics and service systems. In this area, one of Haselkorn’s current PhD students, Robin Mays, has received a three-year National Science Foundation Graduate Fellowship (2012–2016). Campus location: Mary Gates Hall (MGH) Campus room: 241 Event sponsors: Human Centered Design & Engineering, University of Washington Facebook: www.facebook.com… More info: hcde.uw.edu…

  • Nov 6: CEI Interdisciplinary Seminar: Venkat Subramanian, Associate Professor Chemical Engineering, University of Washington

    Thu Nov 6, 2014 4:00 pm - 5:00 pm | Thursday, Nov. 6, 2014, 4 - 5 p.m. PST Model Based Battery Management System (BMS) for Electric Transportation and Renewable Microgrids Lithium ion batteries are a promising technology to reduce the dependence on fossil fuels for transportation and for the creation of resilient and reliable renewable microgrids. However, battery manufacturers overdesign lithium ion batteries used in electric vehicle to ensure safety and life due to the uncertainty of the internal states of the cell. Proactive battery management systems (BMS) and advanced sensing technologies offer an opportunity to significantly reduce the cost and weight of transportation batteries, and circumvent problems arising due to capacity fade and safety concerns. This talk will describe how multiscale electrochemical engineering models, mathematical model reformulation and the use of robust algorithms can alleviate some of these problems to help electrify the transportation industry by improving the range of variables that are predictable and controllable in a battery in real-timewithin an electric vehicle. The use of battery models in a BMS will be analyzed. The interplay between the fundamental depth in modeling, choice of numerical algorithms, and application driven problem formulation will be presented. The validity of implementation in a microcontroller environment for model predictive control (MPC) will be addressed and demonstrated. In addition, preliminary results on aggressive sizing and control strategies for batteries in renewable microgrids will be presented. Bio: Venkat Subramanian is Washington Research Foundation Associate Professor of Chemical Engineering and Clean Energy.Associate Professor at the University of Washington.  He holds a B. Tech, Chemical & Electrochemical Engineering, Central Electrochemical Research Institute (CECRI), Karaikudi, India and a  Ph.D., Chemical Engineering, University of South Carolina, Columbia. Prof. Subramanian’s research focuses on modeling, analyzing and designing cost-effective, energy-efficient and environmentally benign electrochemical systems, in particular devices such as batteries, solar cells, fuel cells and sensors.  His group has developed the fastest algorithm reported in the literature for simulating the performance of lithium-ion batteries.  Prof. Subramanian holds an adjunct appointment in Electrical Engineering, and will be an active collaborator with the Pacific Northwest National Laboratory (PNNL).  Campus location: Electrical Engineering Building (EE1) Campus room: EEB 125 Event sponsors: The Clean Energy Institute Interdisciplinary Seminar Series was established to bring distinguished leaders in the field of clean energy to campus to present their research and meet students, postdocs, and faculty from departments across the Colleges of Arts & Sciences, Engineering, and the Environment. CEI seminars take place regularly throughout the quarter on Thursday afternoons.

  • Nov 6: Forest and Environmental Sciences and Sustainability: A Quest for the 21st Century

    Thu Nov 6, 2014 4:30 pm - 6:00 pm | Thursday, Nov. 6, 2014, 4:30 - 6 p.m. PST UW Civil & Environmental Engineering's 2014 Edward Wenk, Jr. Endowed Lectureship in Technology and Public Policy is entitled: "Forest and Environmental Sciences and Sustainability: A Quest for the 21st Century"Speaker: Thomas H. DeLuca, professor and director of the School of Environmental and Forest Sciences (SEFS) at the University of Washington Reception immediately following For more information about the lecture, see the lecture abstract (PDF). Thomas DeLuca is professor and director of the School of Environmental and Forest Sciences (SEFS) at the University of Washington. A forest soil scientist and ecosystem ecologist, Dr. DeLuca conducts research and directs a School with around 40 faculty members, 160 graduate students, and more than 400 undergraduate students. SEFS operates several facilities on the UW campus, along with four outlying research and education centers. The Edward Wenk, Jr. Endowed Lectureship in Technology and Public Policy brings to the University distinguished practitioners in the field of Civil and Environmental Engineering and Public Policy who engage the context of social, economic, political, and environmental impacts through their knowledge, analytical tools, and professional experience. Campus location: Kane Hall (KNE) Campus room: 210 Event sponsors: UW Department of Civil & Environmental Engineering

  • Nov 10: MolES seminar: Matthew Bush, UW Chemistry

    Mon Nov 10, 2014 2:30 pm - 3:30 pm | Monday, Nov. 10, 2014, 2:30 - 3:30 p.m. PST Ion Mobility Mass Spectrometry of Biomolecular Assemblies Native mass spectrometry is an emerging approach for characterizing the stoichiometry, assembly, and shapes of protein complexes and other biomolecular assemblies in solution. Native mass spectrometry is especially useful for investigating biomolecular assemblies that are challenging to characterize using condensed-phase experiments, including those that are heterogeneous, have large mass, and are membrane bound. I will discuss how my lab has uses ion mobility mass spectrometry and ion/ion chemistry to probe the structures and dynamics of proteins and protein complexes, including fusion proteins between the ATPase from the type II secretion system of vibrio cholera and a scaffold protein that was used to direct its assembly. Bio: Matt Bush pursued his Ph.D. from 2003-2008 with Evan Williams and Richard Saykally at the University of California, Berkeley. During that time he used infrared laser spectroscopy and Fourier-transform ion cyclotron resonance mass spectrometry to investigate zwitterion formation in gas-phase biomolecules and the structural effects of hydration on biomolecular and multiply charged ions. This training in high-performance mass spectrometry and physical chemistry laid the ground work for his continued pursuits using gas-phase techniques to investigate the structures and interactions of biomolecules. In 2008 he joined the laboratory of Carol Robinson FRS DBE at the University of Cambridge and the University of Oxford, during which time he was a Waters Research Fellow, a Junior Research Fellow of Jesus College, University of Oxford, and developed experimental and analytical frameworks for using ion mobility mass spectrometry experiments to accurately characterize the structures of drug-like molecules, peptides, and protein complexes. He joined the chemistry faculty at the University of Washington in 2011, where he is also a member of the Biological Physics, Structure and Design Program and the Molecular Engineering & Sciences Institute. His research group is focused on developing mass spectrometry based approaches for elucidating the structures, assembly, and dynamics of protein complexes. His group applies these approaches to a wide range of biological systems, including those involved in bacterial secretion, regulating protein degradation, and protein homeostasis. Campus location: Johnson Hall (JHN) Event sponsors: The weekly seminar series organized by Molecular Engineering and Sciences Institute provides a forum for bringing national and international leaders in nanoscale science and technology to campus, and for graduate students enrolled in our Dual Ph.D. program in Nanotechnology to present their research. The campus and public are welcome to attend.

  • Nov 11: Veteran's Day (no classes)

    Tue Nov 11, 2014 12:00 am | Tuesday, Nov. 11, 2014 University holiday, no classes Year: 2014 Quarter: Autumn

  • Nov 12: Designing Tailored Motivators with Gary Hsieh

    Wed Nov 12, 2014 4:30 pm - 5:30 pm | Wednesday, Nov. 12, 2014, 4:30 - 5:30 p.m. PST Designing effective incentives is a challenge across many domains, from attracting technology users to nudging behavior change to compensating study participants. Unfortunately, current designs often employ a one-incentive-fits-all approach, assuming that one single reward would work sufficiently for everyone. This overlooks the fact that people are heterogenously motivated; people do not all hold the same values and have the same needs. A single reward, therefore, may not appeal to everyone, and it could also undermine diversity by attracting only certain types of people to participate. An alternative design is to offer individually tailored motivators. While this idea works well in theory, there are many unanswered research questions for this approach to be a viable option. What motivators should we use? Under what circumstances should we use these motivators? How do we design these systems to provide sufficient user control. In this talk, Hsieh will discuss early efforts and challenges in developing tailored motivators. About the Speaker Gary Hsieh is an Assistant Professor of Human Centered Design & Engineering at the University of Washington. His research focuses on studying, designing, and developing technologies that enable people to interact in ways that are efficient and welfare-improving. He was previously an Assistant Professor in Communication and Information Studies at Michigan State University and has conducted research at multiple industry research labs, including Microsoft, IBM, Intel, and Fuji-Xerox. He received his PhD from the Human-Computer Interaction Institute at Carnegie Mellon University and his BS in Electrical Engineering and Computer Science at University of California, Berkeley. He is a recipient of the NSF Career Award. Campus location: Mary Gates Hall (MGH) Campus room: 241 Event sponsors: Human Centered Design & Engineering, University of Washington Facebook: www.facebook.com… More info: hcde.uw.edu…

  • Nov 13: Fall All-college Meeting

    Thu Nov 13, 2014 3:30 pm - 4:30 pm | Thursday, Nov. 13, 2014, 3:30 - 4:30 p.m. PST Agenda coming soon. Reception follows. Campus room: HUB 250 Event sponsors: UW College of Engineering

  • Nov 17: MolES Seminar: Christy Landes, Rice University

    Mon Nov 17, 2014 2:30 pm - 3:30 pm | Monday, Nov. 17, 2014, 2:30 - 3:30 p.m. PST In Search of Concurrence between Biological and Synthetic Single Molecule Structure/Function Practical goals in materials engineering include minimal cost, maximum efficiency, and optimized longevity. As our experimental and theoretical methods to study nature’s molecular-scale design principles have improved, we have begun to understand that one reason nature can be so successful is that her engineering strategy often differs from ours.  hereas humans usually design materials with a single, well-defined function, nature often acts through redundant or degenerate channels that are individually not as efficient, but collectively, and in the face of damage or wear, outperform their synthetic cousins. Obtaining clues from the iological structure-function interplay presents challenges for theory, experiment, and data analysis. When we study one molecule at a time, we eliminate ensemble averaging, thereby accessing any underlying conformational complexity. However, we must develop new methods to increase information content in the resulting low signal-to-noise single-molecule data. Our central question is: Can we take cues from the structure-function interplay and use of cooperative pathways in nature’s biomolecular processes to inform design principles for tailored functional materials applications? The pursuit of answers to this question presents challenges for theory, measurement, and data interpretation. The talk will present insights into the overall question, as well as attempts to overcome some of the innate challenges encountered along the way. Campus location: Johnson Hall (JHN) Campus room: 102 Event sponsors: The weekly seminar series organized by Molecular Engineering and Sciences Institute provides a forum for bringing national and international leaders in nanoscale science and technology to campus, and for graduate students enrolled in our Dual Ph.D. program in Nanotechnology to present their research. The campus and public are welcome to attend.

  • Nov 18: Lecture: Wireless Power for Implantable Devices

    Tue Nov 18, 2014 7:00 pm - 8:30 pm | Tuesday, Nov. 18, 2014, 7 - 8:30 p.m. PST Join us for the third night of the 2014 Engineering Lecture SeriesCutting the Cord: Wireless Power for Implantable Devices Speaker: Joshua Smith, Associate Professor, Computer Science & Engineering and Electrical Engineering You or someone you know may rely on a cardiac pacemaker, heart pump or other implantable device. Powering these common medical devices is challenging. Existing approaches include batteries that must be surgically replaced every few years and cables extending out of the body, which can attract infection. It is becoming increasingly feasible to use wireless signals from a source placed in clothing or furniture—and perhaps even from cellular and television signal towers—to power implanted devices. Learn about emerging wireless technologies that may impact the quality of life for many individuals. Campus location: Kane Hall (KNE) Campus room: 120 Event sponsors: UW College of Engineering and UW Alumni Association Facebook: www.facebook.com… Twitter: twitter.com… More info: engage.washington.edu…

  • Nov 19: Wayfaring and Wandering in a Digital Age with Daniela Rosner

    Wed Nov 19, 2014 4:30 pm - 5:30 pm | Wednesday, Nov. 19, 2014, 4:30 - 5:30 p.m. PST The Hearts and Minds of Data Science Daniela Rosner, HCDE Assistant Professor November 19, 2014 4:30–5:20 p.m. Mary Gates Hall (MGH), room 241 Learn more at hcde.uw.edu/current-issues-in-hcde Campus location: Mary Gates Hall (MGH) Campus room: 241 Event sponsors: Human Centered Design & Engineering, University of Washington Facebook: www.facebook.com… More info: hcde.uw.edu…

  • Nov 24: MolES seminar: Cole DeForest, UW ChemE

    Mon Nov 24, 2014 2:30 pm - 3:30 pm | Monday, Nov. 24, 2014, 2:30 - 3:30 p.m. PST Campus location: Johnson Hall (JHN) Campus room: 102 Event sponsors: The weekly seminar series organized by Molecular Engineering and Sciences Institute provides a forum for bringing national and international leaders in nanoscale science and technology to campus, and for graduate students enrolled in our Dual Ph.D. program in Nanotechnology to present their research. The campus and public are welcome to attend.

  • Nov 27: Thanksgiving (no classes)

    Thu Nov 27, 2014 12:00 am | Thursday, Nov. 27 - Friday, Nov. 28, 2014 University holiday, no classes Year: 2014 Quarter: Autumn

  • Dec 1: MolES Seminar: Scott Phillips, Penn State University

    Mon Dec 1, 2014 2:30 pm - 3:30 pm | Monday, Dec. 1, 2014, 2:30 - 3:30 p.m. PST Polymeric Materials with Amplified Responses to Specific Applied Signals This presentation will describe strategies for creating functional polymeric materials that provide amplified responses to specific stimuli. One approach employs end-capped polymers that depolymerize completely from head-to-tail when the end-cap is removed from the polymer in response to a stimulus. Demonstrated applications of these polymers include shape-shifting materials, plastics that are easily recycled, self-powered pumps, point-of-care diagnostics, as well as controlled release chemistry.       Bio: Scott Phillips is the Martarano Associate Professor of Chemistry at the Pennsylvania State University.  He earned his Ph.D. from Paul A. Bartlett at UC Berkeley in 2004 and trained as a postdoctoral fellow in George Whitesides’ group (Harvard).  He started his independent career at Penn State in 2008.  His research interests include: (i) developing thermally stable detection and signal amplification reagents for use in point-of-care diagnostics; (ii) developing exceedingly inexpensive but high performance diagnostic devices for use in resource poor environments; and (iii) designing new classes of stimuli-responsive plastics that display amplified and autonomous responses for biomedical and environmental applications. He has been recognized for his achievements by the Beckman Foundation, the Camille & Henry Dreyfus Foundation, DARPA (Young Faculty Award), 3M, NSF (CAREER), Popular Mechanics, the Alfred P. Sloan Foundation, Eli Lilly, Thieme Chemistry, and others.        Campus location: Johnson Hall (JHN) Campus room: 102 Event sponsors: The weekly seminar series organized by Molecular Engineering and Sciences Institute provides a forum for bringing national and international leaders in nanoscale science and technology to campus, and for graduate students enrolled in our Dual Ph.D. program in Nanotechnology to present their research. The campus and public are welcome to attend.

  • Dec 1: Human Centered Design & Engineering Master's Info Session

    Mon Dec 1, 2014 5:30 pm - 6:30 pm | Monday, Dec. 1, 2014, 5:30 - 6:30 p.m. PST Join the Department of Human Centered Design & Engineering (HCDE) to learn more about the HCDE Master's degree. All sessions are held from 5:30-6:30 p.m. in Sieg Hall, Room 420, on the University of Washington campus in Seattle. Learn more and apply at hcde.uw.edu/ms. Campus location: Sieg Hall (SIG) Campus room: 420 Event sponsors: Human Centered Design & Engineering (HCDE) Facebook: www.facebook.com… More info: hcde.uw.edu…

  • Dec 3: Designing Technology to Support Self-Experimentation for Health with Julie Kientz

    Wed Dec 3, 2014 4:30 pm - 5:30 pm | Wednesday, Dec. 3, 2014, 4:30 - 5:30 p.m. PST Designing Technology to Support Self-Experimentation for Health Julie Kientz, HCDE Associate Professor December 3, 2014 4:30–5:20 p.m. Mary Gates Hall (MGH), room 241 Learn more at hcde.uw.edu/current-issues-in-hcde Campus location: Mary Gates Hall (MGH) Campus room: 241 Event sponsors: Human Centered Design & Engineering, University of Washington Facebook: www.facebook.com… More info: hcde.uw.edu…

  • Dec 25: Christmas (no classes)

    Thu Dec 25, 2014 12:00 am | Thursday, Dec. 25, 2014 University holiday, no classes Year: 2014 Quarter: Autumn

  • Jan 1: New Year's Day (no classes)

    Thu Jan 1, 2015 12:00 am | Thursday, Jan. 1, 2015 University holiday, no classes Year: 2015 Quarter: Winter

  • Jan 15: CEI Interdisciplinary Seminar: Bruce Dunn, Professor of Materials Science, UCLA

    Thu Jan 15, 2015 4:00 pm - 5:00 pm | Thursday, Jan. 15, 2015, 4 - 5 p.m. PST The Clean Energy Institute Interdisciplinary Seminar Series was established to bring distinguished leaders in the field of clean energy to campus to present their research and meet students, postdocs, and faculty from departments across the Colleges of Arts & Sciences, Engineering, and the Environment. CEI seminars take place regularly throughout the quarter on Thursday afternoons. Campus room: TBD Event sponsors: UW Clean Energy Institute

  • Jan 19: Martin Luther King Day (no classes)

    Mon Jan 19, 2015 12:00 am | Monday, Jan. 19, 2015 University holiday, no classes Year: 2015 Quarter: Winter

  • Jan 21: CEE Career Fair

    Wed Jan 21, 2015 1:00 pm - 4:00 pm | Wednesday, Jan. 21, 2015, 1 - 4 p.m. PST The CEE Career Fair attracts hundreds of CEE  grad and undergrad students as well as pre-engineering students from the College of Engineering.   Students’ interests range from “general civil engineering” to specific areas of engineering emphasis covered by the Department, including construction, transportation, geotechnical, structural, water resources/ hydrology/fluid mechanics, and environmental engineering. Students: The CEE Career Fair is open to all students.  Registration is not required. Employers Register now. A late registration fee of $15 applies after January 7, 2015. Campus location: Student Union Building (HUB) Campus room: North Ballroom Event sponsors: UW Civil & Environmental Engineering More info: www.ce.washington.edu…

  • Jan 21: CEE Career Fair

    Wed Jan 21, 2015 1:00 pm - 4:00 pm | Wednesday, Jan. 21, 2015, 1 - 4 p.m. PST The goal of the CEE Career Fair is to connect students and employers who are interested in civil and environmental engineering.   Typically, hundreds of undergraduate and graduate students attend.   Students’ interests range from “general civil” to specific areas of engineering emphasis covered by the Department including construction, transportation, geotechnical, structural, hydrology/hydrodynamics, and environmental engineering.  For more information and to register online, visit: www.ce.washington.edu…. Also, join us for the Chair’s Happy Hour Reception for employer reps and alumni following the fair.  As is now the tradition, the Chair, Greg Miller, hosts a Happy Hour Reception for attending employer reps and alumni from 4 to 6pm.  Employer reps and alumni are invited to the reception for refreshments, the Chair’s welcome and the State of the Department overview, and to meet and mingle with faculty and other industry reps. Register early for the CEE Career Fair.  Space is limited.  Late registration fee applies after January 7, 2015. If you have any questions, please feel to contact us at ceadvice@uw.edu. Campus location: Student Union Building (HUB) Campus room: South Ballroom

  • Jan 29: CEI Interdisciplinary Seminar: Antonio Jesus Conejo Navarro, Professor of Integrated Systems Engineering, Ohio State

    Thu Jan 29, 2015 4:00 pm - 5:00 pm | Thursday, Jan. 29, 2015, 4 - 5 p.m. PST The Clean Energy Institute Interdisciplinary Seminar Series was established to bring distinguished leaders in the field of clean energy to campus to present their research and meet students, postdocs, and faculty from departments across the Colleges of Arts & Sciences, Engineering, and the Environment. CEI seminars take place regularly throughout the quarter on Thursday afternoons. Campus room: TBD Event sponsors: UW Clean Energy Institute

  • Jan 29: ENGINEERING EXPLORATION NIGHT

    Thu Jan 29, 2015 5:30 pm - 8:30 pm | Thursday, Jan. 29, 2015, 5:30 - 8:30 p.m. PST Registration opens later in autumn quarter. Engineering Exploration Night connects engineering alumni and students to discuss engineering careers and fields. Students meet with a diverse group of industry professionals in a "speed date" format. Alumni have the opportunity to: Be a mentor to students considering the pursuit of a degree in engineering. Share with students your experiences as a professional engineer. Answer students' burning questions about engineering fields and professional careers. The event is open to pre-engineers, freshmen and sophomores and includes dinner. Each year, we seek 30+ engineering alumni from all disciplines. Interested alumni, please contact: Kelly Williams kvw9880@uw.edu 206-221-5072 Campus location: McCarty Hall (MCC) Event sponsors: UW College of Engineering More info: www.engr.washington.edu…

  • Feb 12: CEI Interdisciplinary Seminar: Antoine Kahn, Professor of Electrical Engineering, Pirinceton University

    Thu Feb 12, 2015 4:00 pm - 5:00 pm | Thursday, Feb. 12, 2015, 4 - 5 p.m. PST The Clean Energy Institute Interdisciplinary Seminar Series was established to bring distinguished leaders in the field of clean energy to campus to present their research and meet students, postdocs, and faculty from departments across the Colleges of Arts & Sciences, Engineering, and the Environment. CEI seminars take place regularly throughout the quarter on Thursday afternoons. Campus room: TBD Event sponsors: UW Clean Energy Institute

  • Feb 16: President's Day (no classes)

    Mon Feb 16, 2015 12:00 am | Monday, Feb. 16, 2015 University holiday, no classes Year: 2015 Quarter: Winter