| Friday, Oct 13 |
7.1.1 Biomimetic Cultures |
10:30 AM |
| 13727 |
Equivalent control of microtubule assembly by strain and the extracellular
matrix |
Andrew Putnam; David Mooney |
| 14519 |
Concentration gradients of neurotrophic factors provide axonal guidance |
Cao XUDONG; Molly SHOICHET |
| 14786 |
A Tissue-Engineered Model of a Blood Vessel for he Study of Vascular Biology |
Robert NEREM; Barbara Imberti; Dror Seliktar |
| 14161 |
Automated 3D Tracking of Cancer Cells in Collagen Gels: Quantification of
the Cell Migration and Invasion at the Cellular Level |
Zoe N. Demou; Larry V. McIntire Ph.D. |
| 16365 |
Engineered Matrices for the Musculoskeletal System |
Shelley WINN |
| Friday, Oct 13 |
7.1.2 Cell-Substrate Interactions |
2:00 PM |
| 13909 |
Patterned deposition of mammalian cells, extracellular matrix proteins,
and polyethylene oxide through microfluidic networks and photolithography |
William Jastromb; Sangeeta BHATIA |
| 14677 |
Decoupling the Effect of Growth Factors on Cell Motility and Growth in Advancing
Monolayers Using the Fischer Equation |
Harihara Baskaran; Karen Hamoen; Abbey Perumpanani; Jeffrey MORGAN; Francois
BERTHIAUME |
| 14187 |
Sickle Red Blood Cell Adherence to Endothelium is Stronger for Attachment
under Dynamic Shear Flow |
Stewart MCNAULL; James ECKMAN; Lewis HSU; Timothy WICK |
| 14710 |
Cell Adhesion to Micropatterned Supported Lipid Bilayers |
Lance KAM; Jennifer S Hovis; Li A Kung; Steven G BOXER |
| 14523 |
Using BioMEMS to control cellular microenvironments |
Christopher Chen MDPhD; Joe Tien PhD; John Tan; Celeste Nelson |
| 15242 |
Model Substrates for Controlling and Understanding the Interactions of Cells
with Materials |
Milan MRKSICH |
| Saturday, Oct 14 |
7.1.3 Molecular Regulation of Adhesion |
8:30 AM |
| 14137 |
Electrical Stimulation Enhances Select Cellular/Molecular Functions of Osteoblasts |
Peter SUPRONOWICZ; Dennis Metzger PhD; Bernard Arulanandam PhD; Klaus Ullmann;
Pulickel Ajayan PhD; Rena BIZIOS |
| 13973 |
Mechanical Loading Influences Ligament Fibroblast Behavior |
Adam HSIEH; Jeffrey HO; Li YANG; Robert SAH; Wayne AKESON; Kuo-Li SUNG |
| 13743 |
Stress Fiber ñ Metallic Particle Complex Induces the Inhibition of
Osteoblast Adhesiveness, Cell Proliferation, Viability, and Activates Specific
Gene Activities |
Soon-Young Kwon; Quing-Jun Ma; Tong Lin; Dominique Pioletti P.; Hiroshi
Takei; K-L. Paul Sung |
| 14913 |
Topographic Requirements for Signaling Neutrophil Activation Through L-selectin |
Scott SIMON; David PEARSON |
| 13808 |
A potential role of [Ca2+]i as a down regulator of integrin-mediated tumor
cell migration to type IV collagen |
Louis Hodgson; Cheng DONG |
| 14220 |
Atomic force and total internal reflection fluorescence microscopy for the
study of force transmission in endothelial cells |
Anshu Mathur; William Reichert; George Truskey |
| Saturday, Oct 14 |
7.1.4 Cellular Engineering |
10:30 AM |
| 14200 |
Long-term effect of inflammatory mediators on hepatic function |
Yoon KANG; Francois BERTHIAUME; Martin YARMUSH |
| 14682 |
Development of an in vitro cell culture system for the study of drug metabolism
using encapsulation technologies: Paclitaxel as a model drug |
Susan ROBERTS; Robert Fisher; Louis Roberts |
| 14936 |
Endothelial Cell Responses to Cyclic Pressure |
Hainsworth SHIN; Jiro NAGATOMI; Mary Gerritsen; Rena BIZIOS |
| 14157 |
Effect of Clustering Osteoblastic Cells on Growth and Function |
Aaron Goldstein; Eric Bowerman |
| 14663 |
Tethering Through Selectins Signals Neutrophil Adhesion in Sheared Suspension |
Daniel MCDONOUGH; Eric Hentzen; Rupa Rao; C. Wayne Smith; Scott SIMON |
| 14613 |
Cell-free rolling yields fundamental insights into leukocyte adhesion |
Daniel HAMMER; Stephen Rodgers; Adam GREENBERG; Ray Camphausen |
| Friday, Oct 13 |
7.1P Cellular Engineering I |
12:00 PM - 2:00 PM (Poster Session) |
| 13839 |
Quantitative Analysis of HER2 Expression Level Effects on Receptor Internalization |
Bart HENDRIKS; Henry WILEY; Douglas LAUFFENBURGER |
| 14622 |
Neural Cell Death Following Mechanical Stretch Injury |
Bryan PFISTER; Gang BAO; Timothy WEIHS; Michael BETENBAUGH |
| 13867 |
Modulation of the Spatial Operation of an Autocrine System |
Ann DEWITT; Douglas LAUFFENBURGER; H. Steven Wiley |
| 14914 |
A quantifiable adhesion assay using a spinning disk device to measure the
adherent strength of BCR/ABL transformed cells to a fibronectin matrix |
Jason Wertheim; Daniel Hammer; David Boettiger; Warren Pear |
| 14920 |
Chemotactic Stimulus and F-Actin Dynamics in Human Neutrophils |
Mariam MAGHRIBI; Scott SIMON |
| 13924 |
Controlling Hepatocyte Fate: The Role of Small GTPases Differs Between Hepatocytes
Stabilized By Cell-Cell Versus Cell-Matrix Interactions |
Toshifumi Azuma; Paul Lin; Sangeeta BHATIA |
| 13961 |
Enhanced Potency of Covalently Modified Granulocyte Colony-Stimulating Factor |
Casim SARKAR; Peggy WANG; Douglas LAUFFENBURGER |
| 14244 |
Simulation of cochlear outer hair cell electromotility |
Alexander SPECTOR; Mohammed AMEEN; Aleksander POPEL |
| 14028 |
Trans-epithelial electrical resistance in bronchial epithelial cells: effects
of continuous H<sub>2</sub>O<sub>2</sub> exposure
and KGF |
Kenneth Chapman; William Miller; Christopher Waters |
| Thursday, Oct 12 |
7.2.1 Vascular Cell Mechanics |
10:30 AM |
| 14593 |
Effects of Strain Rate and Magnitude on Endothelial Cell Reorientation Rate |
Jeremiah WILLE; Frank YIN |
| 14423 |
Cyclic strain stimulates intracellular superoxide production in vascular
smooth muscle cells |
George A. VLASTOS; Marc E. Goldschmidt; Dan Sorescu; W. Robert TAYLOR |
| 14579 |
Reducing Endothelial Cell Detachment via Cohesive Failure by Stiffening
Cell Membrane with Cholesterol |
Bernard CHAN; William REICHERT; George TRUSKEY |
| 13403 |
Development of a Micro Tensile Tester for Cells and Its Application to Viscoelastic
Analysis of Bovine Aortic Smooth Muscle Cells |
Takeo MATSUMOTO; Junpei SATO; Mitsunobu YAMAMOTO; Masaaki SATO |
| 13979 |
Homotypic neutrophil adhesion probability assessed by micromanipulation |
Christopher Spillmann; Richard Waugh Ph.D. |
| 14015 |
Effect of Immobilized IL-8 on Neutrophil Rolling and Adhesion |
Jeffrey DiVietro; McRae Smith; Michael Lawrence |
| Thursday, Oct 12 |
7.2.2 Vascular Cell Dysfunction |
2:00 PM |
| 14649 |
Regulation and Adaptation of Shear Stress-Sensitive Ion Channels in Vascular
Endothelial Cellsμ |
Abdul BARAKAT; Deborah LIEU; Pamela PAPPONE |
| 13947 |
Lactosylceramide Mediates the Shear-Induced Superoxide Production in Vascular
Endothelial Cells |
Li-Hong Yeh PhD; Adam M. Kinsey; Subroto Chatterjee PhD; B. Rita Alevriadou
PhD |
| 14370 |
Nitric oxide production by cultured human vein endothelial cells: response
to in vitro simulation of external pneumatic compression |
Guohao DAI; Olga Tsukurov; Michael Chen; Jonathan Gertler; Roger Kamm |
| 13470 |
Increased Adherence of Flowing Monocytes to Cultured Endothelial Cells After
Hypoxia/Reoxygenation: Involvement of Rac-1, ROS and VCAM-1 |
Chi Kin Domingos Ng MS; Kaikobad Irani MD; B. Rita Alevriadou PhD |
| 14480 |
The Role of VLA-4/VCAM-1 in Sickle Red Blood Cell-Endothelium Interactions |
Eileen FINNEGAN; Gilda Barabino |
| 14758 |
Control of the Shape of a Neointima-Like Structure by Blood Shear Stress |
Shu LIU |
| 13994 |
Prostaglandin E<sub>2</sub> (PGE<sub>2</sub>) Response
in MC3T3-E1 Osteoblastic Cells is Dependent Upon Gap Junction Coupling |
Marnie SAUNDERS; Jun YOU; James TROSKO; Hiroshi Yamasaki; Henry DONAHUE;
Christopher Jacobs |
| Thursday, Oct 12 |
7.2.3 Vascular Cell - Cell Adhesive Interactions |
4:00 PM |
| 14087 |
Neutrophil Morphological Regulation of Selectin Binding in Shear Flow |
Eric Park; McRae Smith; Michael Lawrence |
| 14676 |
Leukocyte Rolling and Deformation on P-selectin in Whole Blood |
David SCHMIDTKE; Scott Diamond L |
| 14661 |
IL-8 Dose and ICAM-1 Site Density Determine the Dynamics of Neutrophil Adhesion
Under Fluid Shear |
Aaron Lum; Scott SIMON |
| 13993 |
Platelet Glycoprotein Ibalpha: A Multifunctional Receptor for Tethering
Under Flow Conditions |
Larry McIntire Ph.D; Alcia Schade Ph.D.; Jing-Fei Dong Ph.D; Jose LOPEZ
Ph.D. |
| 12821 |
Immobilized Platelets Support Human Colon Carcinoma Cell Tethering, Rolling
and Firm Adhesion Under Dynamic Flow Conditions |
Owen MCCARTY; Konstantinos KONSTANTOPOULOS |
| 14405 |
The effects of non-linear flow on cell aggregation : Role of spatial and
temporal variations in inter-particle forces |
Harish SHANKARAN; Sriram NEELAMEGHAM |
| Thursday, Oct 12 |
7.2P Vascular Cell - Cell Adhesive Interactions |
12:00 PM - 2:00 PM (Poster Session) |
| 13829 |
Temporal Analysis of Fibroblast Traction and Migration in Tissue Equivalents |
David SHREIBER; Victor BAROCAS; Paul Enever; Mihir Wagle; Robert TRANQUILLO |
| 14189 |
Particle Diameter Influences Receptor - Ligand Mediated Adhesion Under Flow |
Vivek Shinde Patil; Craig Campbell; Yang Yun; Steven Slack; Douglas Goetz |
| 14194 |
Analysis of Selectin Binding to Immobilized Glycosphingolipids under Flow
Conditions |
Monica BURDICK; Konstantinos KONSTANTOPOULOS |
| 14223 |
CD11b/CD18 Coated Microspheres Adhere to Activated Endothelium via Two Distinct
Mechanisms |
Vivek Shinde Patil; Charles Parkos; Douglas Goetz |
| 14231 |
A Web Site Focused on Explaining the Biology and Physics of Cell Adhesion. |
Jao Ou; Brian Good; Vivek Shinde Patil; Douglas Goetz |
| 14743 |
Shear Stress Modulates Platelet-Staphylococcal Interactions |
Julia ROSS; Konstantinos KONSTANTOPOULOS; Owen MCCARTY; Nehal Mohamed |
| 14236 |
PSGL-1 Microsphere Adhesion in Vivo |
Erin Burch; Mohammad Kiani; Vivek Shinde Patil; Douglas Goetz |
| 13987 |
Prostaglandin E<sub>2</sub> (PGE<sub>2</sub>) Response
to Fluid Flow is Independent of Intracellular Calcium Concentration in Osteoblastic
ROS 17/2.8 and RCx16 Cells |
Marnie SAUNDERS; Jun YOU; Clare Yellowley; Henry DONAHUE; Christopher Jacobs |
| Saturday, Oct 14 |
7.4 Minisymposium: Tools for Drug Discovery |
Noon |
| |
Presenters:
Michael Heller, Chief Technology Officer, Nanogen
Salvatore Forenza, Executive Director, Lead Discovery and Early Discovery
Chemistry, Bristol-Meyers Squibb |
| Saturday, Oct 14 |
7.3.1 Mathematical and Computational Modeling in
the Mechanics of Cells I |
2:00 PM |
| 14394 |
Predicting intracellular stress using continuum computational models |
Roger Kamm; Mark Bathe; Anna McVittie |
| 14845 |
Computational Modeling of Short-Term Interval-Force Relations in Single
Cardiac Myocytes |
J. Jeremy Rice; M. Saleet Jafri; Raimond WINSLOW |
| 14924 |
A Continuum-Kinetic Model for Cell Adhesion and Movement |
Narcisse N'DRI; H.S. UDAYKUMAR; Wei SHYY; Roger TRAN-SON-TAY |
| 13537 |
Nonlinear Electromechanical Model for the Cochlear Outer Hair Cell |
Alexander SPECTOR |
| 12362 |
Discrete vs. Continuum Representation of Cell Force |
Victor Barocas |
| 14590 |
Simulation of hydrodynamic interactions between adherent rolling cells |
Michael KING; Daniel Hammer |
| Saturday, Oct 14 |
7.3.2 Mathematical and Computational Modeling in
the Mechanics of Cells II |
4:00 PM |
| 13878 |
FROM SINGLE MOLECULES TO MEMBRANE NETWORK MECHANICS |
Dennis DISCHER; James Lee; Carol Kwok; Philippe Carl |
| 14553 |
A Novel Mechanical Model for the Actin Cytoskeleton |
Christopher HARTEMINK; John HARTWIG; C. DEWEY |
| 14306 |
Computational modeling of the cochlear outer hair cell cytoskeleton |
Alexander SPECTOR; Mohammed AMEEN; Panos CHARALAMBIDES; Aleksander POPEL |
| 14670 |
Brush Border Microvilli: a New Approach for Examining the Hydrodynamic Interaction
with the Actin Cytoskeleton |
Peng Guo; A. M. Weinstein; Sheldon Weinbaum |
| 13959 |
Chondrocyte-Extracellular Matrix Interactions During Osmotic Loading |
Van C. Mow PhD; X. Edward Guo PhD; Christopher CB Wang MS; Clark T. Hung
PhD |
| 14474 |
How do cells sense a transcellular pressure difference?: A combined computational
and experimental approach. |
Anna MCVITTIE; Daniel TSCHUMPERLIN; Jeffery DRAZEN; Roger KAMM |
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